coronary artery disease - definition:
Stenotic arteriosclerotic coronary artery disease
is a narrowing of the coronary arteries caused by atherosclerosis that, when
sufficiently severe, limits the flow of blood to the myocardium (heart
muscle). In its most severe form, it occludes the coronary arteries.
coronary bypass surgery - history:
Early surgical attacks to treat coronary heart
disease include the direct implantation of the internal mammary artery into
the myocardium by Vineberg and Miller in 1951. Largely overlooked is the
first operation for coronary artery disease in which the internal mammary
artery was directly anastomosed to the LAD-coronary artery by Kolesov in
Leningrad in 1964. In May 1967 Favoloro and Effler, at Cleveland Clinic,
started reversed saphenous vein bypass grafting.
what is a coronary artery bypass
graft ?
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Aortocoronary
bypass surgery means that one or more bypass grafts are implanted
between the aorta and the coronary blood vessel. If occlusive vascular
disease limits the blood flow to the heart, the bypass graft bridges the
occluded or diseased heart blood vessel
(coronary artery)
and brings new blood to the heart. Saphenous veins
(from the leg)
or arteries (like the IMA =
internal mammary artery) are commonly used
as grafts for coronary bypass surgery. |
coronary artery bypass surgery
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After thoracotomy
(opening of the chest) the left IMA
(internal mammary artery)
is harvested. Simultaneously, a segment of the saphenous vein
(vein of the leg)
is prepared for the aorto- coronary bypass operation. Intraoperative
photo (left)
showing the heart and the harvested IMA. Photo on the
right
(white circle)
showing the IMA being prepared for bypass grafting. |
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After induction of extra- corporeal
circulation the aorta is x-clamped, the coronary arteries are exposed,
opened and the IMA is anastomosed (sutured) into the coronary artery.
Intraoperative photo (left)
showing the anastomosis of the IMA to the coronary artery. Photo on the
right
showing the IMA-bypass to the coronary artery
(LAD), now
supplying arterial blood to the heart muscle - bypassing the occluded
coronary artery. |
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Demonstrating additional vein grafting:
left:
coronary artery is exposed (<-),
the vein prepared (->).
middle:
the vein is sutured into the coronary artery.
right: the
bypass is finished (->). |
coronary artery bypass surgery -
results
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Annual aortocoronary bypass
operations since 1984 (orange bars)
Included in this data are all re-operations (patients who have undergone
previous coronary bypass surgery before), currently about 11% of all
coronary bypass procedures. The overall perioperative mortality for all
24.888 coronary bypass operations (incl. re-operations) since 1984 in
our clinic: 1.2% |
10 year follow-up of 1.000 consecutive coronary
artery bypass patients in our hospital:
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Freedom from PTCA 10 years after surgery for all
patients is 88.9%. |
Freedom from reoperation 10 years after surgery for all
patients is 91.0%. |
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The 10 year survival after surgery for all patients is
71.9% - split according to age at the time of surgery. |
Patent saphenous vein bypass grafts assessed at
re-coronary angiogram studies during the 10 year follow-up period. |
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